Arteriovenous Malformation Market Poised for Steady Growth, Reaching USD 4,563.64 Million by 2030 with a CAGR of 6.1%
The Arteriovenous Malformation Market is expected to reach USD 4,563.64 Million by 2030 at 6.1% CAGR during the forecast period 2022-2030.
The Arteriovenous Malformation (AVM) market is witnessing significant developments in the healthcare sector, with a focus on innovative treatments for conditions such as cerebral arteriovenous malformation (CAVM). AV malformation refers to abnormal connections between arteries and veins, disrupting the normal blood flow. CAVM specifically involves these malformations in the brain, posing serious health risks. The market's current landscape is marked by a surge in research, technological advancements, and emerging therapies to address the complexities associated with AV malformations.
Market Trends:
Advancements in Interventional Radiology: The AV malformation market has seen a paradigm shift with the advent of cutting-edge interventional radiology techniques. Minimally invasive procedures, such as embolization and endovascular surgery, have gained prominence in treating AV malformations, offering patients a less invasive alternative to traditional open surgeries.
Emerging Therapies and Pharmaceutical Innovations: Pharmaceutical companies are investing heavily in research and development to introduce novel therapeutic options for AV malformations. Targeted drug therapies aim to reduce the size of malformations and improve patient outcomes, providing hope for those with complex cases.
Growing Awareness and Early Diagnosis: Increased awareness about AV malformations, especially CAVM, has led to a rise in early diagnosis. Medical professionals are utilizing advanced imaging technologies to detect malformations at an early stage, enabling timely intervention and preventing potential complications.
Global Collaboration in Research: The AV malformation market presents opportunities for global collaboration in research and development. Collaborative efforts among healthcare institutions, research organizations, and pharmaceutical companies can accelerate the discovery of new treatment modalities.
Patient-Centric Approaches: Tailoring treatments to meet the specific needs of individual patients is gaining prominence. Personalized medicine approaches, including genetic testing and targeted therapies, are anticipated to shape the future of AV malformation management.
Top of Form
Major Key Players:
The Arteriovenous Malformation Companies are Toshiba Medical Systems Corporation (Japan), Carestream Health (U.S.), Nihon Kohden Corporation (Japan), Electrical Geodesics Inc. (U.S.), Fujifilm Holdings (Japan), GE Healthcare (U.S.), Siemens Healthcare(U.S.), Philips Healthcare (U.S.), Shimadzu Corporation (Japan), Masimo Corporation (U.S.), Hologic (U.S.), Esaote (Italy), and others.
Segment Analysis
The global arteriovenous malformation market is segmented on the basis of types, diagnosis, treatment, and end user. On the basis of types, it is segmented into true arteriovenous malformation, occult or cryptic AVM or cavernous malformations, venous malformation, hemangioma, and dural fistula. On the basis of diagnosis, it is segmented into physical examination, blood test, brain scans, and others. Brain scan is further segmented into computerized tomography (CT) scan, Magnetic Resonance Imaging (MRI), magnetic resonance angiography (MRA), and electroencephalography (EEG). On the basis of treatment, the market is segmented into endovascular embolization, neurosurgery and others. On the basis of the end user, it is segmented into hospitals & clinics, research laboratories and others.
Recent Development
In January 2023, Eisai Co., Ltd. and Biogen Inc. jointly declared that the U.S. Food and Drug Administration (FDA) had granted approval for lecanemab-irmb 100 mg/mL injection for intravenous administration via the Accelerated Approval Pathway. Lecanemab-irmb is a humanized immunoglobulin gamma 1 (IgG1) monoclonal antibody designed to target aggregated soluble and insoluble forms of amyloid beta (Aβ). It is indicated for the treatment of Alzheimer's disease (AD). The approval is predicated on Phase 2 data indicating that LEQEMBI decreased the deposition of Aβ plaque in the brain, which is a characteristic feature of Alzheimer's disease. Eisai will expeditiously employ the data recently disclosed from the expansive worldwide confirmatory Phase 3 clinical trial, Clarity AD, to submit a Supplemental Biologics License Application (sBLA) to the FDA in pursuit of conventional pathway approval.
In August 2022, Vaderis Therapeutics AG emerged from covert mode with a clinical-ready drug candidate and an emphasis on allosteric AKT inhibitors, thanks to financial backing from Medicxi. The nascent biotechnology company intends to initiate a proof-of-concept clinical trial to evaluate its principal compound VAD044 in individuals afflicted with Hereditary Hemorrhagic Telangiectasia (HHT). HHT, which is also referred to as Osler-Weber-Rendu Syndrome, is a hereditary condition characterized by the formation of arteriovenous malformations, which are aberrant connections between veins and arteries. Nose, lung, brain, and liver are the organs most frequently impacted by these malformations. The malformations may eventually induce spontaneous hemorrhage. Anemia, iron deficiency, shortness of breath, and seizures are all symptoms of the disease that can negatively impact quality of life. At this time, no pharmaceuticals have been approved by the FDA for the specific purpose of treating HHT. Vaderis aspires to be the first organization to transport a candidate for this disease through the clinic.
Regional Analysis
The Americas dominate the global arteriovenous malformation market owing to the presence of huge patient population, high health care spending, and increasing government support for research & development.
Europe holds the second largest share of the global market. The increasing focus of various government agencies on treating various brain disorders or brain injuries such as epilepsy and depression will have a positive impact on the growth of the market. The growing public awareness will boost the adoption of these devices in the European market.
Asia Pacific is the fastest growing arteriovenous malformation market across the globe. Japan holds a major share of the regional market due to availability of technology and huge healthcare spending. Rapidly developing economy, increasing healthcare expenditure, and government initiatives for research & development will drive the market in China and India over the assessment period.
The Middle East and Africa hold the least share of the global market due to limited availability of medical facilities. The UAE, Saudi Arabia, and Kuwait are expected to drive the Middle East & African market whereas, the African region is expected to witness a moderate growth.
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